SEMENDO-Base
Research Project
			Funding Entity:
AMU Amidex
			Budget (K€):
112
			Status:
Ongoing
			Our role:
Coordinator
			Starting Date:
06/2023
			Ending Date:
06/2026
			Partners:
MEPHI/IHU Méditerranée Infection
			Short Description
Infective endocarditis (IE) is a life-threatening condition with high morbidity and mortality, difficult to diagnose, involving infection of the heart lining and valve destruction with vegetation formation. Early targeted antibiotic treatment can reduce the risk of fatal embolisms caused by vegetation detachment. Despite advances in diagnosis and treatment, IE's impact remains significant. We've developed a novel method using scanning electron microscopy for detailed vegetation analysis, which varies by bacterial species. To overcome current manual, subjective analysis, we aim to employ deep learning for automated, standardized detection and quantification of vegetations to enhance understanding and treatment.