ASDMOD : Modeling complex autistic-like behavior in mice and impact of obesity induced during pregnancy

Research Project

Funding Entity:

ANR

Budget (K€):

540

Status:

Ongoing

Our role:

Partner

Starting Date:

01/2023

Ending Date:

06/2027

Partners:

AMU/LIS UMR 7020, Inmed UMR1249, Institut de Neurobiologie de la Méditerranée, IBDM UMR 7288, Institut de Biologie du Développement de Marseille

Short Description

ASDMOD aims at modelling behaviors of autistic (ASD) mouse models, caused by either genetic mutations, excessive gestational weight gain (GWG, detected today in half of women), or both. It focuses on a non-invasive, longitudinal, and blind behavioral study of male and female autistic mouse models (genetic and environmental models) compared with control mouse (same age, same sex). We thus propose a 3D behavioral analysis pipeline dedicated to the study of temporal series of single actions (individual, dyadic or group actions). This framework will rely on computer vision and deep learning techniques and will consider these actions time series at multiple time-scales.