SEMENDO-Base

Research Project

Funding Entity:

AMU Amidex

Budget (K€):

112

Status:

Ongoing

Our role:

Coordinator

Starting Date:

06/2023

Ending Date:

06/2026

Partners:

MEPHI/IHU Méditerranée Infection

Short Description

Infective endocarditis (IE) is a life-threatening condition with high morbidity and mortality, difficult to diagnose, involving infection of the heart lining and valve destruction with vegetation formation. Early targeted antibiotic treatment can reduce the risk of fatal embolisms caused by vegetation detachment. Despite advances in diagnosis and treatment, IE's impact remains significant. We've developed a novel method using scanning electron microscopy for detailed vegetation analysis, which varies by bacterial species. To overcome current manual, subjective analysis, we aim to employ deep learning for automated, standardized detection and quantification of vegetations to enhance understanding and treatment.